SciDev.Net

This report, published by the Global Forum for Health Research, tracks global investments in health research and development (R&D).

The authors review global targets and commitments for R&D in health and evaluate how well these are being met. They highlight the differences in funding by region, including analyses from Argentina, China and the United States; and provide a breakdown of investments in R&D for cancer and 20 widespread infectious diseases.

They also describe the different sources of R&D funding, providing data on private, public and not-for-profit investments.

The authors discuss the implications of the current funding climate for future health research and make recommendations for improving research agendas, suggesting that R&D investments must match the health needs of developing countries now and in the future.

This report, written by a team of international scientists and published by the UN Environment Programme (UNEP), explores the effects of 'atmospheric brown clouds'(ABCs) on regional climate, agriculture and human health.

ABCs are large plumes of pollutant gases that result from burning fossil fuels and biomass. The authors of the UNEP report examine the spread of ABCs — particularly in Asia — and discuss their likely impacts, including decreases in the Indian summer monsoon rainfall, accelerated glacial retreat and increases in surface ozone.

They suggest that ABCs threaten water and food security in Asia, impact human health and may mask the warming effects of climate change by 20 – 80 per cent. The authors recommend an international response to tackle the twin effects of ABCs and greenhouse gases, and the unsustainable development that underpins them.

This report, published by the Center for International Development at Harvard University and the International Livestock Research Institute in Kenya, asks which institutions and approaches are most effective in using scientific knowledge to inform development strategies.

The authors evaluate five agricultural projects in Africa and Asia and suggest that the best strategies for closing the gaps between knowledge and action include: 'boundary-spanning' efforts such as creating partnerships to improve dialogue between researchers and local communities; 'use-driven' research directed at solving particular problems for particular groups of people; engaging stakeholders from the outset of a project; providing incentives for risk-taking; and improving project management and communication skills.

This report summarises progress towards each of the eight Millennium Development Goals (MDGs) in ten regions, based on data available as of June 2008. Each goal is reviewed, clearly identifying the different targets embedded in each and presenting data to show progress to date and gaps in achievement.

The report emphasises the deep commitment made by the international community to meeting the goals and highlights some of the advances made in areas such as primary school education, health, access to safe drinking water, use of ozone-depleting substances and access to critical drugs.

At the same time, the report points to areas where the goals are unlikely to be met unless additional, or corrective, action is taken. These include child malnutrition, gender parity, sanitation, carbon emissions and international trade negotiations.

A key message is the need to improve developing countries' capacity to produce, analyse and disseminate data. The report points to a number of initiatives aimed at helping this happen.

This report examines ways to increase flows of domestic and foreign investment into clean energy infrastructure and technology in developing countries. It is a synthesis report of the International Institute for Sustainable Development's Clean Energy Investment project.

The authors outline the investment climate in developing countries and suggest ways that policymakers can remove barriers and establish incentives. They suggest there is a need for analytical national studies that highlight the obstacles to clean energy investment — such as a lack of clear guidance on future energy policy, monopoly structures for existing producers, and weak environmental regulation — and a concerted effort at implementing policies to overcome these. The authors also discuss existing international investment law, suggesting ways in which this might foster more clean energy investment.

A policymakers summary of the report is also available.

This report, published by the Food and Agriculture Organization, outlines the current state of the biofuels debate and examines the policies being implemented to support biofuels and those needed to address issues affecting the environment, food security and the poor.

The report begins with a technical overview of the types of biofuels available and then focuses on the economic and policy drivers of liquid biofuels and the short- and long-term prospects of biofuel markets. The environmental impacts of biofuels, together with the impacts on poverty and food security are examined and the policy challenges discussed, including proposals for a better policy framework.

The report suggests that rapid increases in demand for biofuel feedstocks pose an immediate threat to the food security of the urban and rural poor. But it also implies that in the long term, more demand for agricultural commodities may present opportunities for agricultural and rural development. The impact of biofuels on greenhouse gas emissions is found to vary according to location and agricultural practices, and the authors call for more harmonised approaches to assessing the impact of biofuel production on climate change.

This report by the Institute for Development Studies details the results of a pilot project in Bangladesh aimed at developing a screening process for the UK Department for International Development (DFID) to identify and manage climate change impacts on development investments.

The authors highlight predictions that climate change in Bangladesh may lead to stronger cyclones, increased flooding during the monsoon rains and exacerbated drought in the dry season.

They suggest that raising roads and improving drainage could be a cost-efficient way to reduce the impact. Other options recommended for managing risks include paying greater attention to infrastructure design in health, education and private sector development programmes; and to non-structural measures such as livelihood diversification, education and training about disaster risks and adaptation, and improved research and monitoring.

The authors conclude that DFID should support dialogue on disaster risk reduction and climate change adaptation, integrate priorities identified by the Bangladeshi government, increase emphasis for assistance on urban areas, and stimulate a multi-donor dialogue about water issues.

This report is the WHO's official record of data produced by its technical programmes and regional offices in close consultation with countries and in collaboration with researchers and development agencies. The WHO produces the statistics to provide an evidence base for strategies to improve global public health.

The report clearly shows that the global burden of disease is shifting from infectious diseases to non-communicable diseases, with chronic conditions such as heart disease and stroke now being the chief causes of death globally. The shifting trends indicate that leading infectious diseases — diarrhoea, HIV, tuberculosis, neonatal infections and malaria — will become less important causes of death globally over the next 20 years.

The report documents in detail "the levels of mortality in children and adults, patterns of morbidity and burden of disease, prevalence of risk factors such as smoking and alcohol consumption, use of health care, availability of health care workers, and health care financing."

This joint publication between the World Health Organization and the Global Forum for Health Research reveals mental health research capacity in 114 low-income and middle-income countries in Africa, Asia, and Latin America and the Caribbean. The extensive review identified over 10,000 articles, 4,633 mental health researchers and 3,829 other stakeholders. The authors argue that this is "the first systematic attempt to confirm the pressing needs of improving research capacity in mental health".

The publication provides useful details in table and charts, analysed by group of stakeholders and by region, on topics such as: researchers' profiles; priority-setting process; amount and type of research production; services and technical support available to them; courses and trainings offered; funding patterns; and dissemination of research findings. The appendix provides two extensive lists — by country — of policy and practice that resulted from research evidence, as well as research evidence that was never translated into policy and practice.

Nine recommendations indicate how the management of mental health research can be strengthened so that it meets the national needs of the countries as well as contributes to the global fund of knowledge. The authors say their report thus enables evidence-based decision-making in funding and priority setting in the area of mental health research in low-income and middle-income countries.

These consist of two reports: SuRF1(Surveillance of risk factors related to non-communicable diseases: current status of global data) and SuRF2 (Surveillance of chronic disease risk factors: country-level data and comparable estimates).

These reports are the result of a large WHO project to set up for the first time a global database of the prevalence of risk factors for non-communicable diseases collected from WHO member states. The first report is largely a collection of the country profiles; the second analyses the data to produce comparable estimates for risk factor prevalence in the countries. The WHO designed this as an advocacy tool to highlight where primary prevention and health promotion need to be directed.

The eight risk factors were chosen because they are easily measurable and theoretically can be changed through prevention efforts. They are: tobacco and alcohol use, patterns of physical inactivity, low fruit/vegetable intake, obesity (as measured by BMI), blood pressure, cholesterol and diabetes (measured by blood glucose).

The second report presents country-level estimates for overweight/obesity and systolic blood pressure. It also shows the attributable mortality and disease burden from all causes of death due to these overweight and high blood pressure for the 11 most populated countries. 

(See WHO Global InfoBase Online for electronically searchable data contained in the reports http://www.who.int/infobase/surf2/online.html.)

Chronic diseases — heart and lung disease, cancer and diabetes — are having a negative economic impact on both the developed and developing world, says this report, which is why they should be properly addressed by domestic and international policy makers. Compared to the epidemiological evidence on the rise of non-communicable diseases in developing nations, there is little information on how this increase will affect their economies.

This report investigates the demographics of the problem and finds that contrary to popular belief, the disproportionate burden of disease on the elderly does have economic implications. The reason is that though the elderly may not be part of the workforce, they are still consumers and therefore a part of the economic equation.

Whether approaches to tackling chronic diseases are cost-effective or not is a vital issue for countries whose health budgets are already overstretched — the report outlines some of the interventions that offer most bang for buck. The authors point out that strategies that work well in developed countries are not so effective in developing countries, and call for more research to assess what will be appropriate.

This extensive report was one of the first to document the scale of the problem of chronic diseases in developing countries, and crucially, to offer guidance on feasible and practical methods of tackling them.

The document starts by laying out in detail the profiles of chronic diseases in different countries, projections for the future, and how chronic diseases are linked with poverty. It also examines in depth the economic costs of such diseases and the macroeconomic consequences of not tackling them quickly enough. The authors outline interventions — whether community, workplace, or school — that have robust evidence supporting them.

The report ends with a call for a unifying framework of global health experts and stakeholders, in which the government has a key role. It also specifies what policymakers need to do to ensure that measures to tackle chronic diseases are put into action.

The report summarises the results of a survey of African Universities’ experiences in collaborating with scientists and institutions in developed countries. The study was carried out by the Association of Commonwealth Universities to provide background information to support the recent development thrust aimed at strengthening African universities through greater investment and North–South (and South–South) collaboration. It focuses primarily on social sciences and humanities research. The report presents empirical data on institutional goals, resource availability, prevalence and satisfaction with collaborative arrangements, challenges faced by individual researchers, capacity building as well as training and research support.

This paper presents a review of the challenges of international scholarly scientific collaboration. It looks at institutional constraints and points out that the challenges and problems multiply when collaborators come from different countries with differing conditions, resource endowments and institutional structures. It is easier to call for more and better forms of international collaboration than it is to design them. The report asserts that good design is helped by a better understanding of what collaboration is and how it has been carried out. It draws on social research insights to help reduce the transactional, financial, ethical and emotional costs of international linkages and exchange and provides a conceptual framework for thinking about international collaboration issues.

Commissioned by UK Office of Science and Innovation, the report looks at the trend of international scientific collaboration between the United Kingdom and its leading partners. It uses bibliometric data (co-authorship and citations of scientific articles) to capture international scientific collaboration in seven broad research fields, focusing on Australia, Canada, China, France, Germany, India, Japan, UK and the US. The data deals with two time-periods, 1996–2000 and 2001–2005 and the report finds that publication of co-authored articles on scientific collaboration has increased considerably faster than the overall increase in research across the two time-periods. It also finds that countries vary in their ability to collaborate or to benefit from it. The results may have important implications for putting international scientific collaborative arrangements in place.

This report attempts to understand the growing trend of international scientific collaboration as a preferred method of building scientific capacity in developing countries. Before the effects of these trends can be documented, however, there is a need to better define scientific capacity itself. This is relevant not only as an end in itself but also as a means of identifying potential collaborators. The traditional dichotomy of developed and developing countries no longer seems to serve the purpose of increasing useful understanding of these trends. The report attempts to provide a new index of scientific capacity based on an aggregation of several national-level measures and creates a useful taxonomy of countries categorised by scientific capacity. The four classifications arising from this taxonomy are scientifically advanced, proficient, developing, and lagging countries. It examines the trends in output, productivity, collaboration and linkages between and among countries in each of these categories.

This is a thorough and in-depth analysis of the link between media coverage of science stories and the public understanding of science. The 56-page document was prepared for the UK Economic and Social Sciences Research Council by British media experts Ian Hargreaves and Justin Lewis, with the support of PhD student Tammy Spears.

The study, published in 2002, was based on data collected from a seven-month media analysis of over 2,000 science stories from radio, television and the press, and two nationwide surveys. It focuses on climate change, the MMR vaccine and cloning/genetic research.

Key findings include:

• there is a clear link between media coverage and the way people understand science
• only the broad patterns of coverage (whether a story or one side of a controversy receives more or less media attention than another) inform opinions;
• the presence of more scientists in the media does not appear to increase public understanding of science issues; and
• a clear and consistent narrative behind an issue helps generate public engagement.

This study continues the work that Hargreaves began in his 2000 report Who's Misunderstanding Whom? in which he discusses the idea of 'dialogue' with the public regarding science, and the possibility of enforcing a code of practice for science journalists.

The South African press has often been criticised for its lack of science and technology coverage. This is the report of a study which aimed to determine how and to what degree science and technology were reported in a representative sample of the South African press.

The study surveyed the amount of science coverage in 15 South African publications over three months in 2002. Around 1000 science and technology articles were sampled and studied for profiles of the science reporters, tone of reporting, use of visuals, prominence of coverage and of controversies, and the nature of the reported science.

There were a number of key findings:

• under 2 per cent of the editorial content studied was dedicated to science and technology;
• a large number of science articles came from foreign sources, including foreign publications and wire services;
• on average, each of the 15 publications had two science correspondents, although this varied greatly according to the type of publication, and none of the regional publications had dedicated science reporters;
• overall, the tone of reporting was positive, with 42 per cent of the articles appearing to promote the benefits of science;
• contrary to expectations, the majority of science articles did not deal with controversy;
• together, biomedicine, astronomy, HIV/AIDS and technology constituted the majority of coverage (although Mark Shuttleworth's visit to the International Space Station during the sampling period no doubt boosted astronomy ratings).

The report concludes with a recommendation to repeat the study at regular intervals and over longer periods.

The report focuses on the lack of antibiotics in the pharmaceutical pipeline. Until now, it says, problems of resistance have been overcome by the development of new drugs. The older ones, to which bacteria or parasites have become resistant get phased out, and the new effective ones are brought in. But what happens when the cupboard is bare?

After a year's investigation of the problem, the authors say that while all stakeholders have a part to play in reducing the effect of resistance, pharmaceutical and biotechnology companies are best placed to take the lead in developing new drugs. The reason for the slump in production has been the high risk involved in investing large sums of money in drugs that might not yield a high return (especially if the drugs are most needed in poor countries).

Legislative and policy changes are needed to spur the pharmaceutical industry into action, says the report. Changes might include allowing companies to extend the exclusivity period on drug patents if they develop a priority antibiotic, tax incentives for R&D of priority antibiotics, or a guaranteed market (for example, by a government or donor agreeing to buy large quantities of drugs).

This brief, based on an ESMAP report published in 2005, provides a roadmap for developing countries considering large-scale biofuels production.

It proposes sugarcane ethanol as the most commercially viable option, and draws on Brazil's experience to show what has made their industry successful, as well as listing eight conditions that foster success in ethanol production. These include adequately educating farmers, establishing good roads and developing a communication infrastructure.

Although almost 100 countries have started to grow sugarcane, none have yet matched Brazil's success. This brief outlines steps for a global evolution of biofuels production, and suggests ways in which governments can help.